More than 44 million people are suffering from Alzheimer disease worldwide, but no one knows—how to protect from this dreadful mental disorder. However, eating pomegranate can help protect from this old age disease
Scientists have found that gut bacteria make pomegranate metabolites –which may protect against Alzheimer’s disease.
Pomegranate is a rich source of polyphenols, and scientists had long believed that it can protect from the development of Alzheimer’s disease. But they were not sure that which molecule were responsible for this.
A team reports in ACS Chemical Neuroscience that the responsible compounds may be urolithins, which are made when gut bacteria break down the polyphenols in the extract.
The cause of Alzheimer disease and how the research raises hope
In Alzheimer’s disease, amyloid proteins in the brain generate clumps. It acts as a barrier between the blood and brain. A team of scientists led by Navindra Seeram and colleagues Urolithins,a compound found in the polyphenol extracts of pomegranate, could pass through the blood-brain barrier and prevent the formation of fibrils.
Urolithins are anti-inflammatory and neuroprotective compounds that are formed when ellagitannins, a type of polyphenol, are metabolized by gut bacteria.
However, scientists feel that more tests need to be carried out to devise the treatment of Alzheimer disease in humans.
(Source: American Chemical Society News Service)